GW-0742 10mg x 100(EVOLIX)
GW501516
Take 10-20 mg / 45 minutes to 1 hour before training, or once a day or 10-12 hours later and then take a second dose.
Cycle for 12-14 weeks, then set off for 4-6 weeks.
* No PCT required
GW0742 SARM: A New PPAR Agonist which increases muscle mass
Cardarine or GW501516 is one of the most popular SARMs out there. Technically, the Cardarine is not a SARM but a PPAR agonist. However, it’s widely marketed and sold as a SARM, so it’s always categorized as one. The drug is mostly used in cutting cycles. According to multiple trials, Cardarine increases the expression of genes responsible for fat catabolism in the skeletal muscles. In other words, it stimulates your body to breakdown and burn fatty acids. How is this relevant to GW0742, though? Well, GW0472 is said to be an improved version of Cardarine GW501516.
What is GW0742?
GW0742 is a PPAR agonist sold as a Selective Androgen Receptor Modulator. The chemical structure of this drug is very similar to that of Cardarine GW501516. In fact, reports claim that GW0742 was only developed to increase the patent of Cardarine by the manufacturer GlaxoSmithKline.
Users claim GW0742 is more powerful than Cardarine, with some saying it is up to 200X more powerful than GW501516. However, the difference in the structures of the two compounds is very minimal, so the two are probably not that different even in the results produced.
Another problem with GW0742 is that the number of research on it is very low. Even finding studies done on rodents is difficult. All SARMs, in general, have relatively limited clinical research. However, since most of them have been around for a long time, the anecdotal evidence provides lots of details on what users can expect. The same can’t be said on GW0742 because not a lot of people use it. The few that do have only taken it for a short time, so we can’t get reliable information on how to dose it and the potential risks involved. GW0742 is also not very easy to find. This explains why many people stick to Cardarine GW501516 even though GW0742 may be slightly better.
Benefits of GW0742
The benefits of GW0742 are very similar to Cardarine’s.
Fat Loss
Being a PPAR agonist, you can expect an increase in fat loss when taking GW0742. The drug boosts metabolism and stimulates your body to turn to fat for fuel. It also increases the oxidative capacity of the muscles helping you to burn more calories.
GW0742 breaks down adipose in different parts of the body, from the arms and legs to the abdomen.
GW0742 can be a great SARM for bodybuilders looking to shred a few pounds of fat to improve muscle definition. The drug will help you achieve this without attacking your lean muscle mass gains.
Increased Endurance and Energy Levels
A typical weight loss plan leaves people feeling lethargic and fatigued simply because they are following a calorie deficit diet that doesn’t factor in energy requirements. That’s not the case with GW0742. This drug works just like Cardarine to increase your energy levels and endurance by turning fat into energy. It suppresses glucose metabolism and stimulates your body to tap into its fat reserves for energy. The increased oxidative capacity in muscles also improves your stamina and endurance.
GW0742 is very helpful for bodybuilders because energy and stamina are a priority even during cutting cycles.
Reduces Inflammation
GW0742 has some anti-inflammatory properties that can benefit your gut. Although several studies have reported this, scientists are still asking for more clinical trials to understand the potential benefits and uses of GW0742 in treating gut inflammation.
Reduces Total Cholesterol
According to this study, GW0742 can reduce total cholesterol by reversing the transportation of cholesterol. The study reports that GW0742 decreases the reabsorption of cholesterol in the intestines. This means most of the cholesterol remains in the digestive tract, where it ends up getting excreted from the body. The researchers reported that GW0742 works in a similar manner as Ezetimibe, a drug used for treating high blood cholesterol.
The one major drawback of the above study is that it was conducted by scientists who are linked to GlaxoSmithKline, the company that owns the patents of both Cardarine GW501516 and GW0742.
Supports a Healthy Lipid Profile
GW0742 increases the metabolism of lipids in the heart. The same benefit has been observed in Cardarine users.
GW0742 Side Effects
The potential side effects of GW0742 remain a mystery due to the lack of enough clinical trials. Since the drug is very similar to GW501516, we can assume that the risks and side effects are more or less similar. This would mean that GW0742 users may experience skin-related issues like acne and oily skin.
There used to be reports that Cardarine can cause or worsen cancer. Fortunately, additional studies proved that Cardarine does not cause cancer. Animal studies have shown that GW0742, too, does not stimulate cancer growth.
GW0742 has been linked to cardiomegaly. This is a condition where the size of your heart increases due to calcineurin activation. The condition was observed in animal studies involving mice. Whether or not the same can happen to humans remains unknown because we don’t have enough human trials on this drug. Sadly, the mere possibility of developing that condition is enough to scare many people from using GW0742.
GW0742 Dosage and Cycle Guideline
GW0742 dosage and cycle should be similar to Cardarine’s. This means a dosage of between 10 and 25mg per day taken in an 8-week cycle.
The drug has a half-life of 24 hours, so you only need to take it once every day.
As a safety precaution, I recommend you start with 10mg per day even if you’ve used GW501516 before. There is so much we don’t know about GW0742, so don’t risk your health by starting with high dosages.
